Robotic endoscopic suturing
A new world of widely available,
safe and effective treatment for obesity
safe and effective treatment for obesity
Nitinotes is a clinical-stage company developing a revolutionary treatment for obesity.
Its flagship product, the EndoZip™, simplifies and speeds up endoscopic gastroplasty procedures, offering a widely available, minimally invasive, and effective solution for over 700 million patients with obesity class I & II for whom traditional bariatric surgery is not an option.
Clinical overview
Nitinotes is conducting a series of pilot studies in various sites around the world aimed at fortifying both its clinical and economic cases
Ongoing
Health economics study
A new EU multi-center study was launched in 23. The primary objective of this study is to evaluate the efficacy and potential health improvement associated with weight loss in obese patients with T2D and/or hypertension following the EndoZip procedure and lifestyle modifications. Enrolments were completed with 38 patients who have successfully undergone the EndoZip™ procedure and are followed up for 12M.
Feb 2023
Completed
Pilot study
A multi-center (Madrid, Rome, Israel) pilot study was launched in July 2021 with 45 patients. After a 12-month follow-up period, the results show a high safety profile, short learning curve, and excellent usability for the Endozip suturing system, with patients averaging an impressive TBWL of 13.5% @ 12M.
Mar 2019
Completed
FIH study
FIH study in Spain was completed in 2019. Led by Dr. Lopez Nava, Director of the Bariatric Endoscopy Unit at HM Sanchinarro University Hospital, Madrid. The study included 11 patients and showed great results of 16.2% TBWL after a 6-month follow-up period.
Expert physicians share their experiences with EndoZip
“With EndoZip™, you are able to easily reproduce the same reliable suture with no additional effort”
Dr. Ivo Boškoski
"It's not so much expert-dependent like other ESG systems"
Dr. Evzen Machytka
"You can’t do anything wrong with the device or make any significant mistake"
Dr. Jan Kral
"While other systems require at least 20 cases to become proficient, with EndoZip™, it took only 3..."
Dr. Steven Shamah
“The stomach reduction we achieve after the procedure is fantastic”
Dr. Roman Turro
"The suturing automation is really impresive. Everything applies the precise strength for suturing or cinching."
Dr. Gontrand López-Nava
The features and benefits of automated gastroplasty
Simple. Accessible. Scalable
Consistent suture size
and depth in each pass
and depth in each pass
High suture density
& durability
& durability
Reproducible
results
results
Improved offering
for patients and physicians
for patients and physicians
Easy to learn
at any skill level
at any skill level
Single
operator
operator
Shorter
procedure time
procedure time
Improved accessibility
and economics
and economics
About us
Nitinotes is a clinical-stage medical device company based in Caesarea, Israel. Its flagship product EndoZip™, is a novel robotic endoscopic suturing system for safer and simpler gastroscopic restriction for the treatment of obesity.
Backed by clinical success and prominent KOLs, Nitinotes’s fully automated, minimally invasive gastroscopic suturing system provides an effective solution for 85% of the obese population (class 1 and 2 obesity) who do not qualify for bariatric surgery.
Backed by clinical success and prominent KOLs, Nitinotes’s fully automated, minimally invasive gastroscopic suturing system provides an effective solution for 85% of the obese population (class 1 and 2 obesity) who do not qualify for bariatric surgery.
Our team
Marina Dror
Operations Manager
Kobi Pinhassi
QA Manager
Sheffy Harel
Eng. Project Manager
Raz Ben Yaacov
R&D Senior Eng.
Benny Gordon
R&D Senior Eng.
Alon Koren
R&D Eng.
Ohad Cohen
R&D Eng.
Nadav Regev
NPI and Testing Eng.
Areen Masre
NPI Eng.
Nadia Del-Guidice
QA Specialist
Ella Gadetsky
Purchase & Warehouse
Yulia Burmaka
QC
Anna Bitman
Technician
Kostya Averbakh
Technician
Evgeni Mikhno
Technician
Evgenia Abramov-Fisher
Technician
Dikla Gafni
Administrative
Board of directors
Scientific advisory board
Director of Advance Endoscopy, Director of Metabolic and Bariatric Endoscopy, Professor of Medicine, Vice-Chair of Innovation, Mayo Clinic, Rochester, MN
Assistant Professor of Gastroenterology (RTDB), Università Cattolica del Sacro Cuore - Gastroenterology & Digestive Endoscopy at Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Director of Bariatric Endoscopy at Madrid Sanchinarro University Hospital
Head of Bariatric Endoscopy of Mohak Bariatric and Robotics, Scientific Director at Endovitta Institute, Head of Bariatric Endoscopy at EOC
Associate Professor at University of Colorado School of Medicine Director of the Gastroenterology Metabolic and Bariatric Program
Director of Therapeutic and Advanced Endoscopy, Hospital-Weill Cornell Medical Center
Director of Bariatric, Metabolic and Digestive Endoscopy at Centro Medico Teknon Barcelona , national coordinator bariatric endoscopy group (Gettemo) at the national endoscopy society SEED
Associate professor of Interdisciplinary Endoscopy
Department, University Hospital Mannheim, Germany.
Chair Member of the German Working Group on Metabolic
Endoscopy, Chair of the Bariatric Endoscopy Committee
of the World Association IFSO, and Chair Member of the
German Obesity Alliance (DAA).
Department, University Hospital Mannheim, Germany.
Chair Member of the German Working Group on Metabolic
Endoscopy, Chair of the Bariatric Endoscopy Committee
of the World Association IFSO, and Chair Member of the
German Obesity Alliance (DAA).
Our investors
Contact Us
Nitinotes Ltd.
5 Haeshel st, Beit Galileo 2,
P.O Box 3158, Caesarea, 3079815, Israel
Tel. +972.4.8876698
info@nitinotesurgical.com